Cardiac Stress in Septic Shock - Biomarkers, Echocardiography and Outcome

NCT01747187 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2012-12-11

No results posted yet for this study

Summary

Septic shock is a major cause of death in intensive care. Septic shock is often dominated by profound changes in organ functions, of which cardiac failure is one of the most severe. In septic shock, biological markers of cardiac stress are often elevated. It is not known to what extent this indicates structural damage to the heart, or in what way they correlate to echocardiographic signs of heart failure.

Here, cardiac failure in ICU patients with septic shock is studied, using biological markers of cardiac stress, inflammatory parameters and echocardiography.

Investigators hypothesize that biomarkers of cardiac stress correlate with echocardiographic signs of heart failure, and that they can predict an increased risk of death.

Conditions

  • Septic Shock
  • Left Ventricular Systolic Dysfunction
  • Left Ventricular Diastolic Dysfunction

Sponsors & Collaborators

  • University Hospital, Linkoeping

    lead OTHER

Principal Investigators

  • Lina De Geer, MD · University Hospital, Linkoeping

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-10-31
Primary Completion
2014-10-31
Completion
2015-04-30

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01747187 on ClinicalTrials.gov