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HIV Reverse Cholesterol Transport Study

NCT01670968 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2020-03-25

No results posted yet for this study

Summary

Primary Objective:

To examine changes in expression of genes \[particularly ABCA1 and SREBP2\] involved in reverse cholesterol transport (RCT) in monocytes from HIV-infected subjects starting antiretroviral therapy and the different effect of NNRTI and PI based regimens

Secondary Objective:

To examine changes in monocyte intracellular cholesterol content in HIV-infected subjects starting antiretroviral therapy and the different effect of NNRTI and PI based regimens

Conditions

Sponsors & Collaborators

  • Chelsea and Westminster NHS Foundation Trust

    collaborator OTHER

  • University College Dublin

    lead OTHER

Principal Investigators

  • Patrick WG Mallon, FRACP FRCPI PhD · HIV Molecular Research Group, UCD School of Medicine and Medical Sciences. Department of Infectious Diseases, Mater Misericordiae University Hospital and Mater Private Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-09-30
Primary Completion
2020-05-31
Completion
2020-06-30

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01670968 on ClinicalTrials.gov