Dyslipidemia is a metabolic disorder characterized by abnormal blood lipid levels, including LDL cholesterol, HDL cholesterol, and triglycerides. It is often asymptomatic but is a major cardiovascular risk factor because persistent lipid abnormalities promote atherosclerosis and vascular events. Management includes lifestyle interventions and lipid-lowering therapies based on risk.
Eli Lilly, AbbVie, Vertex, Gilead Sciences and Pfizer were identified as pharmaceutical stocks to watch, with Abbott Laboratories and McKesson appearing on a separate seven-stock list.
Enlicitide decanoate demonstrated efficacy in reducing LDL cholesterol levels compared to placebo in patients with atherosclerotic cardiovascular disease history or risk, according to phase 3 CORALreef Lipids trial data.
Clinical studies demonstrate GLP-1 receptor agonists like semaglutide and tirzepatide produce substantial weight loss when combined with lifestyle changes, with patients achieving mean reductions of 14.9% body weight over 68 weeks.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07590167 |
A Study to Evaluate the Safety and Pharmacokinetics of AD-231 Compared to Coadministration of AD-231A, AD-231D and AD-231C |
NOT_YET_RECRUITING | PHASE1 |
| NCT07581028 |
Bioequivalence Study of AJU-C715 and C715R in Healthy Adult Volunteers |
NOT_YET_RECRUITING | PHASE1 |
| NCT07559110 |
Supplementation With Salicornia Extract Rich in Polyphenols (B-Salicornia) to Improve Vascular Health in Patients With Dyslipidemia Who Are Not Candidates for Drug Treatment (Low to Moderate Risk) |
NOT_YET_RECRUITING | NA |
| NCT07552571 |
Goal Commitment and Proactive Health Behavior in Chronic Disease Patients |
RECRUITING | NA |
| NCT07545005 |
Impact of a Produce Prescription Program and Nutrition Education Intervention on Cardiovascular Health in Youth |
NOT_YET_RECRUITING | NA |
| NCT07524101 |
Moderate-Intensity Statin Plus Ezetimibe in CKD and ASCVD |
NOT_YET_RECRUITING | NA |
| NCT07515573 |
Effect of Compound (Cardiol Forte) on Lipid And Glycemic Parameters in Low Cardiovascular Risk Individuals |
NOT_YET_RECRUITING | NA |
| NCT07515560 |
Efficacy and Safety of Baroezet Tablet in Korean Patients With Dyslipidemia: A Prospective Observational Study |
NOT_YET_RECRUITING | |
| NCT07502703 |
Validation of Remote Photoplethysmography (rPPG)-Derived Cardiovascular Parameters Against Standard Clinical Measurements and Risk Scores in a Community |
NOT_YET_RECRUITING | |
| NCT07476248 |
The Non-high-density Lipoprotein Cholesterol (Non-HDL-C) to High-density Lipoprotein Cholesterol (HDL-C) Ratio (NHHR) and Its Association With Occurrence of Diabetic Nephropathy in Patients With Diabetes Mellitus |
NOT_YET_RECRUITING |
