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Reliability of Measuring Conditioned Pain Modulation With the Nociceptive Withdrawal Reflex

NCT01636440 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 39

Last updated 2013-01-21

No results posted yet for this study

Summary

Conditioned pain modulation is the ability of the spine to describe changes in pain perception, if two different painful stimulations take place. The reliability of the conditioned pain modulation has not been studied, the instruments used to measure the conditioned pain modulation are sparse and have proven difficult to use in a well reproductible way. This study is using an existing pain test, relying on the reflex in a muscle after a painful electrical stimulation. We will test 34 healthy volunteers in order to test the reliability of the conditioned pain modulation with the nociceptive withdrawal reflex combined to a ice water test.

Conditions

  • Healthy Volunteers

Interventions

DEVICE

Conditioned Pain Modulation

Measure of the conditioned pain modulation with the nociceptive withdrawal reflex and ice water stimulation

DEVICE

Conditioned Pain Modulation

Suprathreshold electrical stimulation with 1.5 times the mean electrical pain detection threshold

Sponsors & Collaborators

  • Aalborg University

    collaborator OTHER

  • Insel Gruppe AG, University Hospital Bern

    lead OTHER

Principal Investigators

  • Michele Curatolo, MD · University Hosptial Bern

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-06-30
Primary Completion
2012-08-31
Completion
2012-08-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01636440 on ClinicalTrials.gov