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Cognitive Conditioned Pain Modulation

NCT07234123 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2026-01-07

No results posted yet for this study

Summary

This "pain reduces pain" study looks at how the brain reduces pain when a person feels two painful sensations at the same time. There is considerable evidence that the brain can "turn down" pain using natural endogenous pain-control systems. The current CPM study measures whether attentional processes can also make a measurable contribution to pain inhibition alongside neurochemical mechanisms.

Conditions

  • Healthy Participants

Interventions

BEHAVIORAL

conditioned pain modulation

simultaneous stimuli to foot (test stimulus) and wrist (conditioning stimulus)

BEHAVIORAL

test stimulus

single brief stimulus to foot only

Sponsors & Collaborators

Principal Investigators

  • Hunter Hoffman · University of Washington

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-08-09
Primary Completion
2025-05-29
Completion
2025-05-29

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07234123 on ClinicalTrials.gov