Genetic Studies of Non-Alcoholic Fatty Liver Disease
NCT01629095 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 17
Last updated 2020-11-27
Summary
Background:
\- Non-alcoholic fatty liver disease is the most common form of liver disease in the United States. It includes many conditions. Researchers want to study fatty liver disease by looking at people who have liver cirrhosis. They also want to look at people who are or were listed for liver transplants. Genetic studies may provide more information on the causes of these conditions.
Objectives:
\- To study possible genetic causes of non-alcoholic fatty liver disease.
Eligibility:
\- Individuals of any age who have non-alcoholic fatty liver disease and related conditions.
Design:
* Participants will be screened with a physical exam and medical history.
* Participants will provide a blood sample for genetic testing. Liver tissue from a transplant or biopsy may also be studied.
* Participants may also be asked to have an imaging study of the liver. This imaging study may be an x-ray or magnetic resonance imaging.
* No treatment will be provided as part of this research study.
Conditions
- Non-Alcoholic Steato-Hepatitis
- Liver Cirrhosis
- Non-Alcoholic Fatty Liver Disease
Sponsors & Collaborators
-
National Human Genome Research Institute (NHGRI)
lead NIH
Principal Investigators
-
Paul S Kruszka, M.D. · National Human Genome Research Institute (NHGRI)
Eligibility
- Min Age
- 1 Month
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-04-23
- Primary Completion
- 2017-01-09
- Completion
- 2017-01-09
Countries
- United States
Study Locations
More Related Trials
-
Identification of Mutations Responsible for Rare Familial Skin Diseases by Next Generation Sequencing
NCT02509650 ·Status: UNKNOWN
-
Clinical Integration of Genetic Risk Assessment in Family Medicine
NCT00339794 ·Status: COMPLETED
-
Genetic Testing and Phenotypic Characterization of Severely Obese Pediatric and Adult Volunteers
NCT02849977 ·Status: COMPLETED
-
Genetic Variants Associated With the Risk of Gall Stones and Cirrhosis.
NCT06679738 ·Status: NOT_YET_RECRUITING
-
Observational Study of Advanced Data Analytics in Genetic Conditions
NCT05657405 ·Status: RECRUITING
-
Next Generation to Identify Genetic Causes of Disease in Patients Participating in NICHD Clinical Protocols
NCT01375543 ·Status: COMPLETED
-
Studies of Families With Hereditary Cataracts
NCT00001609 ·Status: COMPLETED
-
Analyzing Genes That May Increase the Risk of Developing High Blood Pressure
NCT00549991 ·Status: COMPLETED
-
Physicians' Understanding of Human Genetic Variation
NCT00339924 ·Status: COMPLETED
-
Prospective Lung Transplant Database for Genetic Research
NCT00339209 ·Status: COMPLETED
-
Finding Genes for Rare Diseases
NCT02724995 ·Status: WITHDRAWN
-
Genetic Analysis of Human Hereditary Hearing Impairment
NCT00001606 ·Status: TERMINATED
-
APOL1 Genetic Testing in African Americans
NCT05656261 ·Status: RECRUITING
-
Implications of Maternal 45,X Mosaicism as a Secondary Genomic Finding Following Cell-Free DNA Sequencing During Pregnancy: A Deep Phenotype Study
NCT05548881 ·Status: WITHDRAWN
-
Genes Involved in Lipid Disorders
NCT02311335 ·Status: COMPLETED
-
Association of Genes to Resistance to Weight Loss in Obese Patients
NCT00858221 ·Status: COMPLETED
-
Genetic Analysis of Uncommon Disease Presentations in Non-US Populations
NCT06595940 ·Status: RECRUITING
-
Genomics of Primary Sclerosing Cholangitis (PSC)
NCT01161992 ·Status: COMPLETED
-
Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF)
NCT01088217 ·Status: UNKNOWN
-
Genetic Analysis of Congenital Diaphragmatic Disorders
NCT01243229 ·Status: COMPLETED
-
A Study to Compare Genetic Variations of IGF-I and IGF-II
NCT01329523 ·Status: COMPLETED
-
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network
NCT02450851 ·Status: RECRUITING
-
Genetic Origin of Lipid Disorders
NCT00277121 ·Status: UNKNOWN
-
Alzheimer's Disease Genetics Study
NCT00064870 ·Status: RECRUITING
-
Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex
NCT00001452 ·Status: COMPLETED