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Genetic Epidemiology of Primary Biliary Cirrhosis (PBC)

NCT01161953 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1500

Last updated 2025-09-29

No results posted yet for this study

Summary

Primary Biliary Cirrhosis (PBC) is a progressive liver disorder of unknown cause. Current evidence suggests that genes, the genetic material we inherit from our parents, in combination with environmental factors, likely play an important role in the development of PBC.

This study is being done to investigate whether genes make people more likely to develop PBC. Discovery of these proposed genes will help us better understand how PBC developes, and subsequently, to apply new approaches for its prevention, diagnosis and treatment.

Conditions

  • Primary Biliary Cirrhosis

Interventions

GENETIC

Genetic Analysis

Perform Genome Wide Association Studies.

Sponsors & Collaborators

Principal Investigators

  • Konstantinos N Lazaridis, M.D. · Mayo Clinic

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-03-31
Primary Completion
2025-07-31
Completion
2025-07-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01161953 on ClinicalTrials.gov