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Quality Assessment Creatinines in Plasma and Urine

NCT01575392 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 181

Last updated 2012-04-11

No results posted yet for this study

Summary

In clinical practice the 24-hour creatinine clearance is often used to obtain an impression of renal function. However, the glomerular filtration rate is considered to be the best indicator of renal function. For practical and financial purposes, GFR is often estimated by means of serum creatinine based equations. These equations are also used in internation guidelines to define and classify chronic kidney disease. Therefore, accurate creatinine measurements are important to make reliable estimates of renal function. However, previous research has revealed a large variability in creatinine measurements using different measuring methods. In this study the investigators aim to establish the degree of variability in different methods to measure creatinine in a heterogenous group of Caucasian people with and without renal function loss and the influence of this variability on renal function estimating equations and the 24-hour creatinine clearance.

Conditions

Sponsors & Collaborators

  • Medical Research Foundation, The Netherlands

    lead OTHER

Principal Investigators

  • I Drion, MD · Diabetes Centre, Isala Clinics, Zwolle, the Netherlands

  • Henk JG Bilo, Prof · Diabetes Centre, Isala Clinics, Zwolle, the Netherlands

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-06-30
Primary Completion
2011-01-31
Completion
2011-01-31

Countries

  • Netherlands

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01575392 on ClinicalTrials.gov