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Comparison of Dexmedetomidine and Remifentanil Infusion During CABG

NCT01572454 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 77

Last updated 2013-12-25

No results posted yet for this study

Summary

We are trying to investigate whether intraoperative dexmedetomidine infusion could decrease the incidence of intraoperative hypokalemia and arrhythmia, and myocardial injury in patients undergoing off-pump coronary artery bypass graft, and trying compare these effects with those of remifentanil infusion.

Conditions

  • Coronary Artery Bypass Graft
  • Hypokalemia
  • Cardiac Arrhythmia
  • Dexmedetomidine
  • Remifentanil

Interventions

DRUG

Dexmedetomidine infusion

Dexmedetomidine infusion 0.2 mcg/kg/hr during anesthetic induction 0.3 - 0.7 mcg/kg/hr during the surgery

DRUG

Remifentanil infusion

Remifentanil infusion 0.05 - 0.3 mcg/kg/min during the anesthetic induction and surgery

Sponsors & Collaborators

  • Samsung Medical Center

    lead OTHER

Principal Investigators

  • Hyun Sung Cho, MD, PhD · Samsung Medical Center

  • Won Ho Kim, MD · Samsung Medical Center

  • Young Tak Lee, MD, PhD · Samsung Medical Center

Study Design

Allocation
RANDOMIZED
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-03-31
Primary Completion
2012-12-31
Completion
2012-12-31

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01572454 on ClinicalTrials.gov