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Analgesia After Total Knee Replacement Surgery

NCT01489631 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 81

Last updated 2015-06-08

No results posted yet for this study

Summary

Postoperative pain after total knee replacement surgery is difficult to treat. Mobilisation and hospital discharge might be delayed. Recent research shows that intra-articular infiltration with local anesthetics and perioperative prescription of gabapentin can improve outcome.

Objective of the study: Comparison of mobilisation speed and postoperative NRS-scores of patients after total knee replacement surgery which is treated with epidural analgesia or peroperative infiltration of the knee. Appraisal of the value of gabapentin for reduction of postoperative opiate consumption.

Conditions

  • Total Knee Arthroplasty

Interventions

DRUG

naropin

ropivacaine 0,2%, 3x 50 ml during surgery

DRUG

marcaine

bupivacaine 0,125%

DRUG

sufentanil

sufentanil 1mcg/ml

DRUG

neurontin

gabapentin 600 mg pre-operative 3 dd 300 mg

Sponsors & Collaborators

  • St. Antonius Hospital

    lead OTHER

Principal Investigators

  • Leon Timmerman, MD · Anesthesiologist

  • Louis N Marting, MD · Orthopedic surgeon

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-03-31
Primary Completion
2014-04-30
Completion
2014-04-30

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01489631 on ClinicalTrials.gov