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Morphine Consumption in Joint Replacement Patients, With or Without Gabapentin Treatment

NCT01307202 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 101

Last updated 2014-11-20

No results posted yet for this study

Summary

Total knee arthroplasty is amongst the most painful procedures postoperatively, and pain management can be a challenge. Different measures have been introduced to manage severe postoperative pain int hese patients. Previous studies have investigated gabapentin in acute postoperative pain and demonstrated reducted pain, postoperative morphine consumption, morphine related side effects, and postoperative pain scores. To date, this analgesia adjunct has yet to be investigated in total joint arthroplasty patients.

Conditions

  • Post Operative Pain
  • Total Knee Replacement

Interventions

DRUG

Gabapentin

600mg of Gabapentin will be given orally preoperatively and 200mg for 3 times a day after surgery for 3 days

DRUG

Placebo

Placebo will match the the gabapentin pill and will be given orally.

Sponsors & Collaborators

Principal Investigators

  • Manyat Nantha-Aree, MD · Hamilton Health Sciences Corporation

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
19 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-10-31
Primary Completion
2011-02-28
Completion
2011-02-28

Countries

  • Canada

Study Locations

More Related Trials

Entities

Drugs
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01307202 on ClinicalTrials.gov