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Effect of Perioperative Oral Pregabalin in Total Knee Replacement

NCT06187922 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2024-01-03

No results posted yet for this study

Summary

This interventional randomized control trial aim to determine efficacy and safety of Oral pregabalin in improving after surgery pain control in patients undergoing total knee replacement surgeries under regional anesthesia. We'll compare the efficacy of pregabalin between two groups, pregabalin group and control group on the basis of their opioid consumption after knee operation.

Conditions

  • Postoperative Pain

Interventions

DRUG

Pregabalin 75mg

Group pregabalin will receive cap pregabalin 75mg as premedication and will continue as B.D dose for 72 Hrs.

PROCEDURE

adductor canal block

Both group will receive ultrasound guided Adductor canal block with bupivacaine 0.2% 20-30ml and dexmedetomidine 1mcg/Kg

Sponsors & Collaborators

  • Bahrain Defence Force Hospital

    lead OTHER

Principal Investigators

  • Mohammed Al Muharraqi, FRCS,FDSRCS · Bahrain Defence Forces Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-01
Primary Completion
2025-06-30
Completion
2025-07-30

Countries

  • Bahrain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06187922 on ClinicalTrials.gov