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iMRI Guided Resection in Cerebral Glioma Surgery

NCT01479686 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 321

Last updated 2021-10-19

No results posted yet for this study

Summary

Many clinical studies have been reported on iMRI, however, their evidence levels are relatively not as good as what people hope they will be. Based on the available literature, there is, at best, level 2 evidence that iMRI-guided surgery is more effective than conventional neuronavigation-guided surgery.

The investigators aim to do a single center prospective randomized triple-blind controlled clinical trial to assess the effect of 3.0T high-field intraoperative MRI-guided glioma resection on surgical efficiency and progression-free survival of malignant glioma to provide a level 2A evidence for its clinical application.

Conditions

Interventions

PROCEDURE

iMRI

3.0TiMRI guided resection in adults with glioma

PROCEDURE

conventional neuronavigation

conventional neuronavigation guided resection in adults with glioma

Sponsors & Collaborators

  • Huashan Hospital

    lead OTHER

Principal Investigators

  • Liang-fu Zhou, M.D. · Huashan Hospital

  • Ying Mao, M.D., Ph.D · Huashan Hospital

  • Jin-song Wu, M.D., Ph.D · Huashan Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-09-30
Primary Completion
2018-09-30
Completion
2021-03-31

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01479686 on ClinicalTrials.gov