MedTrace Logo

Generation of Haploid Stem Cells From Human Germ Cells

NCT01454765 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2013-12-11

No results posted yet for this study

Summary

Human cells are diploid (contain a double set of chromosomes). The diploid genome is complex and therefore limits genetic research approaches in biomedical models. To overcome this problem experimental generation of haploid stem cells has been done in animals. The investigators aim at generating haploid stem cells from human germ cells that are a useful tool in genetic research and screening.

Conditions

  • Induced Pluripotent Stem Cells

Interventions

OTHER

generation of stem cells

Collected germ cells will be cultured in medium. The germ cell cultures will be infected with reprograming factors. Rare colonies with characteristic stem cell morphologies will be expanded.

Sponsors & Collaborators

  • Rambam Health Care Campus

    lead OTHER

Principal Investigators

  • Itay Maza, M.D · Rambam Health Care Campus

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-12-31
Primary Completion
2014-12-31
Completion
2015-08-31

Countries

  • Israel

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01454765 on ClinicalTrials.gov