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Changes in the Distribution of Mitochondria During Oocyte Maturation

NCT01501292 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2011-12-29

No results posted yet for this study

Summary

Cytoplasmatic maturation is an important event in the general maturation of of the oocyte. Mitochondria is one of the major organelles involved in the process of cytoplasmatic maturation. The aim of this study is to investigate the presence and distribution of the mitochondria in the cytoplasma of immature oocytes that are retrieved in the routine in-vitro maturation cycle with intracytoplasmatic sperm injection (ICSI). These oocytes will not undergo ICSI because of their immaturity. Usually, they are discarded. In addition to these immature oocytes the investigators shall also investigate the mitochondria in mature oocytes that underwent ICSI but did not become fertilized and are discarded.

Conditions

Interventions

OTHER

Fixation and staining

Fixation and staining by MitiTracker Green FM

OTHER

Observation by laser microscopy

Observation with Laser scanning confocal microscopy

Sponsors & Collaborators

  • Hillel Yaffe Medical Center

    lead OTHER_GOV

Eligibility

Min Age
18 Years
Max Age
44 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-01-31
Primary Completion
2012-04-30
Completion
2012-04-30

Countries

  • Israel

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01501292 on ClinicalTrials.gov