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Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos

NCT07227116 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 280

Last updated 2025-11-12

No results posted yet for this study

Summary

This study aims to evaluate the reproductive potential of embryos classified as "complex aneuploid" (involving three or more abnormal chromosomes) or "chaotic" (six or more abnormal chromosomes) through preimplantation genetic testing for aneuploidy (PGT-A). Specifically, we seek to determine whether embryos initially reported as having multiple chromosomal abnormalities might still have the potential for normal chromosomal composition, the opportunity for transfer, and ultimately, the potential to achieve a live birth through re-biopsy and reanalysis.

Key Information:

This portion of the study seeks your consent for the re-biopsy and genetic reanalysis of the embryos only. It does not yet include consent for potential future transfer.

Participation remains completely voluntary, and your decision will not affect your current or future care.

We deeply appreciate your support and commitment to advancing fertility research.

Conditions

  • Complex Aneuploidy
  • Chaotic Aneuploidy

Sponsors & Collaborators

  • Shady Grove Fertility Reproductive Science Center

    lead OTHER

Principal Investigators

  • Kate Devine, MD · Shady Grove Fertility

  • Benjamin S Harris, MD, MPH · Shady Grove Fertility

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-11-01
Primary Completion
2026-04-30
Completion
2026-06-30

Countries

  • United States
  • Chile

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07227116 on ClinicalTrials.gov