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Effects of Chimeric Natriuretic Peptide Versus Placebo in Stable Heart Failure and Moderate Renal Dysfunction

NCT01407900 · Status: WITHDRAWN · Phase: PHASE1 · Type: INTERVENTIONAL

Last updated 2014-06-17

No results posted yet for this study

Summary

The overall aim is to conduct a human physiologic study to assess the renal and neurohumoral effects of CD-NP vs placebo in older subjects with stable chronic systolic heart failure and moderate renal dysfunction.

Conditions

Interventions

DRUG

CD-NP

CD-NP as a four hour infusion at 10 ng/kg/min IV

DRUG

5% Dextrose in Water

four hour infusion IV

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • John A. Schirger

    lead OTHER

Principal Investigators

  • John Schirger, MD · Mayo Clinic

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-01-31
Primary Completion
2014-02-28
Completion
2014-02-28

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01407900 on ClinicalTrials.gov