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Prevalence of Decreased Corneal Sensation in Patients With Chronic Inflammatory Demyelinating Polyneuropathy

NCT01379833 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 18

Last updated 2019-06-25

No results posted yet for this study

Summary

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a demyelinating chronic progressive or relapsing neuropathy believed to be secondary to an autoimmune response against peripheral nerve antigens.5 We have observed two patients with CIDP with decreased corneal sensation who also suffered neurotrophic corneal ulcers and severe visual loss in the affected eyes. We want to explore the relationship of CIDP and corneal sensitivity. Our hypothesis is that people with CIDP have decreased corneal sensation compared to those without. We plan to perform a prospective study measuring corneal sensation in patients (proposed n=10) with CIDP and without to determine (1) if a difference exists in patients with CIDP compared to controls and (2) the magnitude of the difference. If a difference is detected in corneal sensitivity in patients with CIDP, this awareness amongst physicians and patients may help prevent blinding complications.

Conditions

Sponsors & Collaborators

  • Dent Neurological Institute, Buffalo, NY

    collaborator UNKNOWN

  • Fichte, Endl & Elmer Eyecare

    collaborator OTHER

  • State University of New York at Buffalo

    lead OTHER

Principal Investigators

  • Surbhi Bansal, M.D. · Ross Eye Institute, University at Buffalo

  • Sangita Patel, M.D. PhD. · Ross Eye Institute, University at Buffalo

  • Thomas Elmer, M.D. · Fichte, Endl & Elmer

Eligibility

Min Age
18 Years
Max Age
110 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-05-31
Primary Completion
2013-12-31
Completion
2013-12-31

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01379833 on ClinicalTrials.gov