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Retrospective Study: Hip Fractures in Diabetic Patients

NCT01379690 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1162

Last updated 2012-02-23

No results posted yet for this study

Summary

Type 2 DM patients are at increased risk of falls as a consequence of long term hyperglycemic complications including retinopathy and neuropathy, and also as a result of hypoglycaemic therapy. Values of A1C \<= 7% has been shown to increase the risk of falls in elderly T2DM patients .

Increased fall risk may explain why T2DM patients are at increased risk of hip fractures , despite having a higher bone mineral density as compared to non-T2DM patients. Given the high morbidity and mortality (25% mortality in 1st year post-fracture) associated with hip fractures , all care must be given to prevent hip fractures in T2DM patients.

There is controversial data on T2DM medications and fracture risk. Vestergaard showed that use of metformin and sulphonylureas decreased the risk of all fractures, while there was there was a similar trend with insulin.

The present study sought to evaluate the relationship between A1c values and the risk of fractures in treated patients with T2DM.

Conditions

Interventions

OTHER

HBA1C

Used level of HBA1C as a reflection of glycaemic control of the cases and controls

Sponsors & Collaborators

  • Changi General Hospital

    lead OTHER

Principal Investigators

  • Troy H Puar, MRCP · Changi General Hospital

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-04-30
Primary Completion
2011-06-30
Completion
2011-06-30

Countries

  • Singapore

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01379690 on ClinicalTrials.gov