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Changes in Arterial Stiffness and Endothelial Glycocalyx in Patients With Poorly Controlled Diabetes Mellitus Type 1 or Type 2 After Optimization of Antidiabetic Medication.

NCT03010956 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2018-10-11

No results posted yet for this study

Summary

Arterial stiffness is associated with increased risk for cardiovascular disease. Moreover, the integrity of endothelial glycocalyx plays a vital role in vascular permeability, inflammation and elasticity. The purpose of this study is to investigate changes in arterial stiffness and endothelial glycocalyx thickness in patients with poorly controlled diabetes mellitus type 1 or type 2 after glycemic control by optimal medication.

Conditions

Sponsors & Collaborators

  • University of Athens

    lead OTHER

Principal Investigators

  • Ignatios Ikonomidis, MD · 2nd Cardiology Department, University of Athens, Greece

  • George Pavlidis, MD · 2nd Cardiology Department, University of Athens, Greece

  • Vaia Lambadiari, MD · 2nd Department of Internal Medicine, University of Athens, Greece

  • Fotini Kousathana, MD · 2nd Department of Internal Medicine, University of Athens, Greece

  • Constantinos Tymbas, MD · 2nd Cardiology Department, University of Athens, Greece

  • George Dimitriadis, MD · 2nd Department of Internal Medicine, University of Athens, Greece

  • John Lekakis, MD · 2nd Cardiology Department, University of Athens, Greece

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-11-30
Primary Completion
2017-06-30
Completion
2017-11-30

Countries

  • Greece

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03010956 on ClinicalTrials.gov