Stress Testing Compared to Coronary Computed Tomographic Angiography in Patients With Suspected Coronary Artery Disease

Summary

The use of coronary computed tomographic angiography(CTA)is rapidly increasing, but there is lack of data which supports their use in the initial evaluation of patients who are asymptomatic or mildly symptomatic. The hypothesis underlying this proposal is that the use of stress-rest myocardial perfusion imaging (MPI) as an initial test for the evaluation of asymptomatic or mildly symptomatic patients who are at intermediate risk of coronary events will result in less further non-invasive and invasive testing and result in reduced costs, without adversely affecting clinical outcomes in the short term.

Conditions

• Coronary Artery Disease

Interventions

OTHER

Coronary CTA

Coronary CTA using standard protocols

OTHER

Stress MPI SPECT

Stress MPI using standard protocols

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Bab El Oued

  collaborator OTHER

• Hospital Italiano Garibaldi,Rosario ARGENTINA

  collaborator UNKNOWN

• Pontificia Universidad Catolica de Chile

  collaborator OTHER

• Fu Wai Hospital, Beijing, China

  collaborator OTHER

• Instituto de Cardiologia,Bogota D.C. COLOMBIA

  collaborator UNKNOWN

• Instituto de Cardiologia y Cirugia Cardiovascular,LA Habana CUBA

  collaborator UNKNOWN

• University Hospital Ostrava

  collaborator OTHER

• Indian Institute of Public Health, India

  collaborator OTHER

• Università degli Studi di Brescia

  collaborator OTHER

• Universidad Nacional Autonoma de Mexico

  collaborator OTHER

• University Medical Centre Ljubljana

  collaborator OTHER

• Ankara University

  collaborator OTHER

• International Atomic Energy Agency

  collaborator OTHER_GOV

• All India Institute of Medical Sciences

  lead OTHER

Principal Investigators

• Ganesan Karthikeyan, MD,DM,MSc · All India Institute of Medical Sciences

• Salah E Bouyoucef · Centre Hospitalier Universitaire de Bab El-Qued

• Jorge Cachero · Hospital Italiano Garibaldi

• Rodrigo J Fernández · Universidad Católica de Chile

• Zuo X He · Fu Wai Hospital, Beijing, China

• Claudia Teresa G Villamil · Instituto de Cardiologia

• Amalia T Peix González · Instituto de Cardiologia y Cirugia Cardiovascular

• Otakar Kraft · University Hospital

• Niveditha Devasenapathy · Indian Institute of Public Health

• Davide Farina · Universita di Brescia

• Aloha Meave · Universidad Nacional Autonoma de Mexico

• Barbara G Salobir · University Medical Centre

• Borut Jug · University Medical Centre

• Elgin Ozkan · Ankara University

• Maurizio DONDI · International Atomic Energy Agency

• Ravi KASHYAP · International Atomic Energy Agency

• Diana PAEZ · International Atomic Energy Agency

Study Design

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

21 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2011-07-31

Primary Completion

2014-06-30

Completion

2014-12-31

Countries

• India

Study Locations