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Meta-Analysis of Stress Myocardial Perfusion Imaging

NCT03180060 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 23051

Last updated 2017-06-08

No results posted yet for this study

Summary

Background: Detection of coronary artery disease (CAD) is important due to its high prevalence and its medical and economic implications. Purpose: A systematic review of the diagnostic performance of stress echocardiography (Echo), SPECT, cardiac magnetic resonance (CMR), CT Perfusion (CTP) and PET versus invasive coronary angiography (ICA) or fractional flow reserve (FFR) using hierarchical summary ROC (HSROC) methods. Data Sources: MEDLINE, EMBASE and SCOPUS for literature published in English or Spanish from January 1970 to December 2015. Study Selection: For inclusion, studies had to meet the Cochrane guidelines, had to evaluate the sensitivity and specificity methods, and use ICA and/or FFR. Only those studies with STARD methodology ≥60% were included. Data Extraction: Ten investigators extracted patient and study characteristics and 4 resolved any disagreements.

Conditions

  • Coronary Disease
  • Echocardiography
  • Fractional Flow Reserve, Myocardial
  • Hemodynamics
  • Humans
  • Magnetic Resonance Imaging
  • Myocardial Perfusion Imaging
  • Perfusion
  • Predictive Value of Tests
  • Single Photon Emission Computed Tomography
  • Positron Emission Tomography
  • Multidetector Computed Tomography
  • Echocardiography, Stress
  • Coronary Angiography

Sponsors & Collaborators

  • American British Cowdray Medical Center

    lead OTHER

Principal Investigators

  • Lilia M Sierra-Galan, MD, MCvT · American British Cowdray Medical Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-08-03
Primary Completion
2016-06-30
Completion
2016-06-30

Countries

  • Mexico

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03180060 on ClinicalTrials.gov