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Regional Fat Depots and Insulin Resistance

NCT01336777 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 166

Last updated 2024-12-04

No results posted yet for this study

Summary

The biological basis for insulin resistance associated with obesity is unknown. By studying equally-overweight/obese individuals who are either insulin resistant or insulin sensitive, the investigators will compare characteristics of fat tissue to test several hypotheses: 1) impaired differentiation and fat storage in the subcutaneous fat depot characterize insulin resistant individuals, who have, as a result, fat in other tissues like liver and muscle, as well as more fat circulating in the blood; 2) inflammation is greater in visceral and/or subcutaneous adipose tissue depots in insulin resistant individuals as compared with insulin sensitive individuals.

Conditions

Sponsors & Collaborators

  • University of California

    collaborator OTHER

  • National Institutes of Health (NIH)

    collaborator NIH

  • Stanford University

    lead OTHER

Eligibility

Min Age
39 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-08-31
Primary Completion
2013-05-31
Completion
2013-05-31

Countries

  • United States

Study Locations

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Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01336777 on ClinicalTrials.gov