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Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome

NCT01246739 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2024-04-10

No results posted yet for this study

Summary

Incidental findings of adrenal tumours,"incidentalomas", occur in 1-5 % in the general population and 10-25 % of these patients will exhibit biochemical mild hypercortisolism. Although the patients do not have clinical signs of classical Cushing's syndrome, they have an increased risk for hypertension, dyslipidemia, diabetes mellitus, osteoporosis and obesity.

The hypothesis of the study is, that surgery of the adrenal adenoma responsible for the increased secretion of cortisol, will in part cure or ameliorate the metabolic syndrome.

Conditions

  • Adrenal Tumour With Mild Hypercortisolism

Interventions

PROCEDURE

Adrenalectomy

Adrenalectomy (open or laparoscopic)

Sponsors & Collaborators

  • Region Skane

    lead OTHER

Principal Investigators

  • Anders OJ Bergenfelz, MD, PhD · Department of Surgery, Skåne University Hospital, Lund, Sweden

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-06-30
Primary Completion
2024-02-29
Completion
2024-02-29

Countries

  • Denmark
  • Norway
  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01246739 on ClinicalTrials.gov