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Metabolic Effects of Acute Cortisol Withdrawal in Adrenal Failure

NCT00442390 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2007-03-01

No results posted yet for this study

Summary

Effects of adrenal steroids is generelly drawn from studies of hypercortisolism. The effects of physiological cortisol substitution and withdrawal is studied and related to the clinical syndrome of adrenal insufficiency.

Conditions

  • Addison Syndrome

Interventions

DRUG

hydrocortisone substitution therapy versus withdrawal

Sponsors & Collaborators

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Jens Juel Christiansen, PhD · University of Aarhus

  • Claus H Gravholt, MD · University of Aarhus

  • Christian B Djurhuus, PhD · University of Aarhus

  • Per Iversen, PhD · University of Aarhus

  • Jens S Christiansen, Professor · University of Aarhus

  • Ole Schmidt, Professor · University of Aarhus

  • Jørgen Weeke, Professor · University of Aarhus

  • Jens OL Jørgensen, MD · University of Aarhus

  • Niels Møller, Professor · University of Aarhus

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-01-31
Completion
2003-01-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00442390 on ClinicalTrials.gov