Cushing's Syndrome Before and After Treatment (CORRECT)
NCT05521529 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 20
Last updated 2025-04-04
Summary
The purpose of this study is to prospectively study patients with Cushing's syndrome before and after treatment, with a special emphasis on physical function, quality of life, and circadian rhythms.
The hypotheses are:
* Cushing's syndrome negatively impacts health-related quality of life (HRQoL) and physical functioning
* Cushing's syndrome is associated with altered circadian rhythms at the whole body level and in peripheral target tissues.
* These complications partially reverse following disease control.
Conditions
- Cushing Syndrome
Interventions
- OTHER
-
no intervention, as this is an observational study
no intervention
Sponsors & Collaborators
-
Aarhus University Hospital
collaborator OTHER -
University of Aarhus
lead OTHER
Principal Investigators
-
Jens Otto Lunde Jørgensen, Professor · AARHUS UNIVERSITY HOSPITAL, Medical Research Laboratory
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-02-16
- Primary Completion
- 2028-10-31
- Completion
- 2032-11-30
Countries
- Denmark
Study Locations
More Related Trials
-
A Study to Confirm Recurrent or Persistent Cushing's Syndrome in Patients With Signs or Symptoms of Hypercortisolemia
NCT00796783 ·Status: TERMINATED
-
Long Term Post Operative Follow-Up of Cushing Syndrome
NCT00029952 ·Status: COMPLETED
-
Study of Depression, Peptides, and Steroids in Cushing's Syndrome
NCT00004334 ·Status: UNKNOWN
-
Effects of Metyrapone in Patients With Endogenous Cushing's Syndrome
NCT02297945 ·Status: COMPLETED ·Phase: PHASE3
-
The Accuracy of Late Night Urinary Free Cortisol/Creatinine and Hair Cortisol in Cushing's Syndrome Diagnosis
NCT02791698 ·Status: UNKNOWN
-
Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome
NCT03604198 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Long-Term Follow-Up of Survivors of Pediatric Cushing Disease
NCT03831958 ·Status: RECRUITING
-
A Study of the Efficacy and Safety of CORLUX in the Treatment of Endogenous Cushing's Syndrome
NCT00569582 ·Status: COMPLETED ·Phase: PHASE3
-
Extension Study to Assess the Safety and Efficacy of Pasireotide in Participants With Cushing's Disease
NCT00171951 ·Status: COMPLETED ·Phase: PHASE2
-
Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion
NCT00422201 ·Status: TERMINATED ·Phase: PHASE2
-
Preoperative Bexarotene Treatment for Cushing's Disease
NCT00845351 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Cushing's Disease Complications
NCT02568982 ·Status: COMPLETED
-
Safety and Efficacy of LCI699 in Cushing's Disease Patients
NCT01331239 ·Status: COMPLETED ·Phase: PHASE2
-
Long Term Safety and Efficacy of Pasireotide s.c. in Patients With Cushing's Disease
NCT02310269 ·Status: COMPLETED
-
Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome
NCT01246739 ·Status: TERMINATED ·Phase: NA
-
Non-interventional Study on Osilodrostat in Patients With Endogenous Cushing's Syndrome
NCT05382156 ·Status: ACTIVE_NOT_RECRUITING
-
Open-label Treatment in Cushing's Syndrome
NCT03621280 ·Status: COMPLETED ·Phase: PHASE3
-
Study of the Efficacy and Safety of Pasireotide s.c. +/- Cabergoline in Patients With Cushing's Disease
NCT01915303 ·Status: TERMINATED ·Phase: PHASE2
-
Metabolic Effects of Acute Cortisol Withdrawal in Adrenal Failure
NCT00442390 ·Status: COMPLETED ·Phase: NA
-
Hydrocortisone Replacement in Patients With Secondary Adrenal Insufficiency (SUPREME CORT)
NCT01546922 ·Status: COMPLETED ·Phase: PHASE4
-
Updated Diagnostic Cortisol Values for Adrenal Insufficiency
NCT05149638 ·Status: RECRUITING ·Phase: NA
-
The Factors Associated With the Recurrence in Patients With Cushing Disease
NCT02233335 ·Status: COMPLETED
-
Compassionate Use of CORLUX® (Mifepristone) in the Treatment of Signs and Symptoms of Endogenous Cushing's Syndrome
NCT01371565 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy of Different Dose Levels of Pasireotide in Patients With de Novo, Persistent or Recurrent Cushing's Disease
NCT00434148 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Cortisol on Physical Exertion in Patients With Primary Adrenal Failure
NCT01847690 ·Status: UNKNOWN ·Phase: PHASE2