Zinc and the Synthesis of Zinc Binding Proteins (Protocol B)
NCT01221129 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 10
Last updated 2011-09-20
Summary
The specific aim of this protocol is to examine differential expression of specific mRNAs and proteins that occur when the dietary intake of zinc is acutely reduced below the dietary requirement for a period of ten days.
Conditions
- Zinc Deficiency
Interventions
- OTHER
-
Acclimation
11 mg Zn/day as a controlled intake level
- OTHER
-
Dietary zinc depletion
\< 1 mg Zn/day achieved by providing a liquified diet of defined nutrient content
- OTHER
-
Dietary zinc repletion
15 mg Zn/day as a daily supplement plus normal habitual diet without restriction
Sponsors & Collaborators
-
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
collaborator NIH -
University of Florida
lead OTHER
Principal Investigators
-
Robert J Cousins, Ph.D. · University of Florida
Eligibility
- Min Age
- 21 Years
- Max Age
- 35 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2009-10-31
- Primary Completion
- 2010-03-31
- Completion
- 2010-03-31
Countries
- United States
Study Locations
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