Familial Myeloproliferative Disorders
NCT00666289 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 17
Last updated 2017-09-05
Summary
Myeloproliferative disorders occur in families, thus giving rise to the theory that it is a genetic disease that may be caused by an abnormal gene in the DNA that can be passed from one generation of family members to another. DNA can be gathered from family members through blood samples and the investigators will investigate (through DNA testing) to see if there are abnormal genes that may be responsible for causing the MPDs. Understanding which genes are responsible for causing MPDs can help develop ways to identify people who may be at risk for developing an MPD, allow for the development of better treatments, possibly a cure, or even prevent the development of MPDs.
Conditions
- Polycythemia Vera
- Essential Thrombocythemia
- Idiopathic Myelofibrosis
Sponsors & Collaborators
-
Myeloproliferative Disorders-Research Consortium
collaborator NETWORK -
National Cancer Institute (NCI)
collaborator NIH -
Icahn School of Medicine at Mount Sinai
lead OTHER
Principal Investigators
-
Josef Prachal, MD · Myeloproliferative Disorders-Research Consortium
Eligibility
- Min Age
- 7 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-03-31
- Primary Completion
- 2015-01-20
- Completion
- 2015-06-20
Countries
- United States
- Italy
Study Locations
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