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Effect of Beta Blockade on Left Ventricular Remodeling and Function in Moderate to Severe Asymptomatic Aortic Regurgitation

NCT01157572 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2014-09-25

No results posted yet for this study

Summary

The primary objective of this study is to evaluate the effect of beta-blocker on left ventricular (LV) remodeling in asymptomatic patients with moderate to severe aortic regurgitation.

Conditions

  • Aortic Valve Insufficiency

Interventions

DRUG

Metoprolol

Patients with moderate to severe aortic valve insufficiency will be randomized to Metoprolol

DRUG

Placebo

Patients with moderate to severe aortic valve insufficiency will be randomized to Placebo

Sponsors & Collaborators

  • University Ghent

    collaborator OTHER

  • University Hospital, Gentofte, Copenhagen

    collaborator OTHER

  • University Hospital, Akershus

    collaborator OTHER

  • Haukeland University Hospital

    collaborator OTHER

  • Oslo University Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-08-31
Primary Completion
2014-08-31
Completion
2014-09-30

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01157572 on ClinicalTrials.gov