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Effect of Beta Blocker Treatment on Endothelial Function in Patients With Type 2 Diabetes or Chronic Heart Failure

NCT00497003 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2007-10-15

No results posted yet for this study

Summary

The aim of this study is to evaluate the effect of the two different beta blockers metoprolol and carvedilol on endothelial function in patients with either type two diabetes or chronic heart failure.

Hypothesis: 1\* Carvedilol compared to metoprolol has a favourable effect on endothelial function.

2\* Carvedilol compared to metoprolol has a favourable effect on insulin stimulated endothelial function.

The study is conducted as an open parallel group study. Endothelial function and insulin stimulated endothelial function was evaluated before and after a two months treatment period with either of the two beta blockers.

Conditions

  • Endothelial Function
  • Beta Blocker

Interventions

DRUG

Treatment with either metoprolol or carvedilol

Sponsors & Collaborators

  • Danish Heart Foundation

    collaborator OTHER

  • Bispebjerg Hospital

    lead OTHER

Principal Investigators

  • Christian Torp-Pedersen, MD, DSc · Department of Cardiology, Bispebjerg Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2004-02-29
Completion
2007-10-31

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00497003 on ClinicalTrials.gov