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Periodontal Disease and P. Gingivalis in Rheumatoid Arthritis

NCT01156155 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 617

Last updated 2023-11-02

No results posted yet for this study

Summary

Periodontitis (PD) has been postulated to be a risk factor for the onset and progression of rheumatoid arthritis (RA). Recent reports suggest that infection with Porphyromonas gingivalis (P. gingivalis), a major oral pathogen in PD, could play a pivotal role in the development RA. The objective of this study is to examine the relationship of PD and P. gingivalis infection with the risk and severity of RA.

Conditions

Interventions

RADIATION

Digital xray of jaw and teeth

one time xray of jaw and teeth

PROCEDURE

Blood draw

Three to four tablespoons of blood drawn.

OTHER

questionnaires

completed questionnaires regarding patient's health and functional ability.

PROCEDURE

Periodontal Examination

Periodontal examination including measurement of gum pockets with a probe. Bacterial samples taken.

OTHER

Bilateral digital xray of hands

One time digital xray of hands

Sponsors & Collaborators

  • Dallas VA Medical Center

    collaborator FED

  • Washington D.C. Veterans Affairs Medical Center

    collaborator FED

  • VA Salt Lake City Health Care System

    collaborator FED

  • University of Nebraska

    lead OTHER

Principal Investigators

  • Ted R Mikuls, MD, MSPH · University of Nebraska

Eligibility

Min Age
19 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-07-14
Primary Completion
2018-08-30
Completion
2018-08-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01156155 on ClinicalTrials.gov