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Association Between Periodontitis and the Level of Anti-citrullinated Protein Antibodies in Rheumatoid Arthritis

NCT05706493 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 36

Last updated 2026-01-13

No results posted yet for this study

Summary

the relationship between rheumatoid arthritis and periodontal disease is crucial and has been explained via a complex interplay of genetic, environmental, and hormonal factors that influence the host immune tolerance leading to both disease characteristics. The aim of this study is to clinically investigate the correlation between the levels of anti-citrullinated protein antibodies (ACPAs) in gingival crevicular fluid before and after non-surgical periodontal treatment and the severity of periodontal disease and rheumatoid arthritis in rheumatoid arthritis (RA) patients

Conditions

Sponsors & Collaborators

  • Misr International University

    lead OTHER

Principal Investigators

  • Zainab Hafez, Lecturer · Lecturer, faculty of oral and dental medicine misr international university

  • Yahia Hassan, Lecturer · Lecturer, faculty of oral and dental medicine misr international university

  • Shahinaz Al ashiry, asso.Prof · Associate Professor, faculty of oral and dental medicine misr international universit

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-03-01
Primary Completion
2025-01-01
Completion
2025-02-01

Countries

  • Egypt

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05706493 on ClinicalTrials.gov