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Skeletal Muscle Dysfunction in Rheumatoid Arthritis (RA)

NCT02535832 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2023-03-27

No results posted yet for this study

Summary

Muscle strength helps determine a person's quality of life and functional independence. Patients with rheumatoid arthritis often suffer from muscle weakness and a pre-diabetic condition called insulin resistance.

By doing this study, the investigators hope to learn why patients with rheumatoid arthritis (RA) suffer from muscle weakness.

Conditions

Interventions

DRUG

Pioglitazone

Pioglitazone CT Scan DXA scan Needle muscle biopsy

DRUG

Placebo

Placebo CT Scan DXA scan Needle muscle biopsy

Sponsors & Collaborators

  • Ohio State University

    lead OTHER

Principal Investigators

  • Beatriz Hanaoka, MD MPH · Ohio State University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
35 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-09-30
Primary Completion
2022-10-31
Completion
2022-10-31
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02535832 on ClinicalTrials.gov