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Exploring the Causes of Clubfoot Using Magnetic Resonance Imaging, MRI

NCT01088828 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 35

Last updated 2015-11-05

No results posted yet for this study

Summary

The purpose of this study is to:

1. compare structural variations observed in the calf and foot of the clubfoot mouse model(pma)with human clubfoot patients antenatally and postnatally;
2. identify features that might be used in future large scale studies to delineate a subtype of human clubfoot associated with lack of response to standard 'Ponseti' manipulation treatments.

Conditions

  • Clubfoot

Interventions

OTHER

Magnetic Resonance Imaging (MRI) of calf and foot

Detailed 3-D comparison of MRI scans of children with clubfoot and controls without clubfoot in utero, in untreated infants and in older children who have been treated.

Sponsors & Collaborators

  • University of Aberdeen

    lead OTHER

Principal Investigators

  • Zosia H Miedzybrodzka, MBChB, PhD · University of Aberdeen

  • Simon L Barker, FRCS, MD · NHS Grampian Health Board

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-05-31
Primary Completion
2011-05-31
Completion
2011-05-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01088828 on ClinicalTrials.gov