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Effect of Glucosamine on Joint Structure and Quality of Life (JOG)

NCT00377286 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 201

Last updated 2011-06-14

No results posted yet for this study

Summary

The goal of this study is 1) to develop a biomarker of of cartilage synthesis by determining if there is a relationship between changes in the status of knee cartilage and the amount of a biomarker called CTX-II in urine. 2) We will also characterize people who have experienced cartilage loss and/or reduced functional ability using performance tests and a questionnaire. 3) The administration of glucosamine in a beverage for six months will be used to promote the alteration in cartilage status and improve function in people with mild to moderate joint pain. A secondary goal will be to assess the effect of glucosamine on the skin in a small subset of women.

Conditions

Interventions

DIETARY_SUPPLEMENT

Glucosamine (a dietary supplement)

1500 mg in 16 oz lite lemonade, once per day for 6 months

OTHER

16 oz lite lemonade

16 oz lite lemonade 1 time daily for 6 months

Sponsors & Collaborators

  • University of Pittsburgh

    lead OTHER

Principal Investigators

  • John Jakicic, PhD · University of Pittsburgh

  • C. Kent Kwoh, M.D. · University of Pittsburgh

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
35 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-09-30
Primary Completion
2008-05-31
Completion
2008-05-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00377286 on ClinicalTrials.gov