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A Comprehensive Study to Isolate Tumor-initiating Cells From Human Epithelial Malignancies

NCT01060319 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2019-04-18

No results posted yet for this study

Summary

We hypothesize that all human malignancies harbour a subpopulation of tumor initiating cells/cancer stem cells (CSCs) that drives tumor development and potentially recurrence or metastasis of the disease. The primary aim of this study is to develop strategies for prospective isolation/enrichment of CSCs from human tumors of different tissue origins. In addition, we will characterize the signaling pathways and/or tumor specific antigens that are specific for CSCs, in order to specifically target these CSCs as the endpoint of this study.

Conditions

  • Bladder Cancer
  • Skin Cancers
  • Bladder (Urothelial, Transitional Cell) Cancer
  • Bladder (Urothelial, Transitional Cell) Cancer Resectable (Pre-Cystectomy)

Sponsors & Collaborators

Principal Investigators

  • Irving L. Weissman M.D. · Stanford University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-12-31
Primary Completion
2014-12-31
Completion
2014-12-31

Countries

  • United States

Study Locations

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Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01060319 on ClinicalTrials.gov