Circulating Tumor Cells (CTC) in Cancer
NCT04520672 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 3000
Last updated 2025-03-12
Summary
This observational study with circulating tumor cells (CTC) count, isolation and analysis at several time points during disease progression is to investigate the role and biology of CTCs and clusters of CTCs in different cancer types. It also evaluates the role of CTCs as biomarkers, and aims at the identification of key signaling networks that are active in CTCs.
Conditions
Interventions
- OTHER
-
Blood samples
Blood samples (3 ethylenediaminetetraacetic acid (EDTA) tubes with a volume of 7.5 ml blood each) will be processed for CTC isolation and characterization, ranging from molecular analysis to culture and drug screen.
- OTHER
-
Samples from tumor draining vessels
In case of tumor resection, 3 EDTA tubes (5 ml) will be withdrawn from the tumor draining vessels for CTC isolation and characterization, ranging from molecular analysis to culture and drug screen.
Sponsors & Collaborators
-
University Hospital, Basel, Switzerland
lead OTHER
Principal Investigators
-
Marcus Vetter, PD Dr. med. · Kantonsspital Baselland, Liestal
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-10-01
- Primary Completion
- 2030-08-31
- Completion
- 2030-08-31
Countries
- Switzerland
Study Locations
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