Cancer Stem Cell Markers and Prognostic Markers in Circulating Tumor Cells
NCT01286883 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 33
Last updated 2018-08-20
Summary
The study will enroll patients with metastatic colorectal cancer receiving chemotherapy. A total of approximately 22 cc of blood will be drawn during various chemotherapy infusions. Additional proposed laboratory studies may unravel important biological insights into the relationship of circulating tumor cell genomic and genetic profiles as they compare to the primary tumors. Additionally the investigators hope to gain an understanding of potential subgroups of patients that have very high numbers of circulating tumor cells or those with early relapse of circulating tumor cells after early reduction of circulating tumor cell numbers.
Conditions
Sponsors & Collaborators
-
Milton S. Hershey Medical Center
lead OTHER
Principal Investigators
-
Wafik S El-Deiry, MD, PhD · Penn State College of Medicine, Penn State Milton S. Hershey Medical Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-02-28
- Primary Completion
- 2014-02-28
- Completion
- 2014-09-30
Countries
- United States
Study Locations
More Related Trials
-
Tumor Phenotypes and Correlation to Clinical Outcomes in Cancer
NCT00283530 ·Status: TERMINATED
-
Examining Blood and Tissue Samples to Identify Diagnostic Markers in Patients With Metastatic Cancer Undergoing Tumor Removal
NCT05530759 ·Status: RECRUITING
-
Culture of Circulating Tumor Cells Isolated From Cancer Patients With Metastatic Disease
NCT02781025 ·Status: COMPLETED
-
Study of Previously Collected and Stored Tissue Samples From Patients Previously Enrolled in a Completed National Cancer Institute Clinical Trial
NCT00904514 ·Status: TERMINATED
-
Memory Phenotype and PD-1 Inhibition Response in Oral Cancer
NCT03862066 ·Status: TERMINATED
-
Cell-Free DNA and RNA in Blood fromMetastatic Prostate Cancer Patients
NCT02853097 ·Status: TERMINATED
-
Detecting Abnormal Blood Clotting in Patients With Metastatic Cancer Undergoing Surgery
NCT00096590 ·Status: COMPLETED
-
Genomic and Proteomic Profiling Targets Influenced Treatment in Metastatic Breast Cancer
NCT02470819 ·Status: WITHDRAWN ·Phase: NA
-
Liquid Biopsy in Monitoring the Therapeutic Efficacy of Targeted Therapy in Advanced/Metastatic Gastric Cancer
NCT02610218 ·Status: UNKNOWN
-
Phase II Study Using Genomic & Proteomic Profiling to Influence Treatments for Patients With Metastatic Breast Cancer
NCT02008994 ·Status: TERMINATED ·Phase: PHASE2
-
Circulating Tumor DNA in Predicting Outcomes in Patients With Stage IV Head and Neck Cancer or Stage III-IV Non-small Cell Lung Cancer
NCT02245100 ·Status: COMPLETED
-
Studying Genes in Samples From Younger Patients With Desmoplastic Small Round Cell Tumor Registered on COG-D9902 or COG-ABTR01B1
NCT01430637 ·Status: COMPLETED
-
Study of Hair Samples From Patients With Cancer
NCT00899691 ·Status: COMPLETED
-
Studying Tumor Tissue Samples From Patients Who Have Undergone Surgery for Localized Kidney Cancer
NCT00908739 ·Status: WITHDRAWN
-
Detection of Oncogenic Tumor Mutations in the Urine and Blood of Lung and Colorectal Cancer Patients
NCT02186236 ·Status: COMPLETED
-
Collection of Circulating Tumor Cells From the Peripheral Blood of Metastatic Breast Cancer Patients
NCT02904135 ·Status: COMPLETED
-
Collection of Blood, Bone Marrow, Tumor, or Tissue Samples From Patients With Cancer to Study Drug Resistance
NCT00026663 ·Status: COMPLETED
-
Studying DNA in Tumor Tissue Samples From Patients With Localized or Metastatic Osteosarcoma
NCT01062438 ·Status: COMPLETED
-
Biopsies of Cancer Patients for Tumor Molecular Characterization
NCT01061944 ·Status: COMPLETED
-
Microarray Analysis of Gene Expression and Identification of Progenitor Cells in Lung Carcinoma
NCT00568906 ·Status: TERMINATED
-
Biomarkers in Predicting Response to Treatment in Patients With Newly Diagnosed Stage III or Stage IV Head and Neck Cancer Treated With Carboplatin, Paclitaxel, and Radiation Therapy
NCT00898430 ·Status: TERMINATED
-
Circulating Tumor DNA to Monitor the Efficacy of Total Neoadjuvant Therapy for Rectal Cancer
NCT05356585 ·Status: WITHDRAWN
-
Biomarkers in Predicting Response to Chemotherapy in Patients With Advanced or Metastatic Melanoma Previously Treated With Carboplatin and Paclitaxel With or Without Sorafenib Tosylate
NCT01209299 ·Status: COMPLETED
-
Collecting and Storing Blood Samples From Patients With Cancer
NCT00900120 ·Status: WITHDRAWN
-
Biomarkers and Clinical Features of Metastatic Breast Cancer in Patients Treated With CDK4/6 Inhibitors
NCT04526587 ·Status: RECRUITING