The Cyclocapnic Method for Measurement of Chemosensitivity
NCT01049256 · Status: UNKNOWN · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 45
Last updated 2010-01-14
Summary
We aim to test our method for measuring chemosensitivity (the ventilatory response to a change in carbon dioxide), which uses sinusoidal carbon dioxide stimuli.
Hypotheses:
* Carbon dioxide sensitivity is dependent on the cycle time over which we administer the gas (frequency).
* Chemoreflex gain decreases as deadspace increases.
Conditions
- Periodic Breathing
- Heart Failure
Interventions
- OTHER
-
carbon dioxide
sinusoidal carbon dioxide administration
Sponsors & Collaborators
-
Imperial College London
lead OTHER
Principal Investigators
-
Darrel P Francis, MD · Imperial College London
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2008-01-31
- Primary Completion
- 2010-04-30
- Completion
- 2010-10-31
Countries
- United Kingdom
Study Locations
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