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Multi-parameters'Change Process During Dehydration Therapy on Brain Edema Patients.

NCT03828032 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2019-07-24

No results posted yet for this study

Summary

This study aims to investigate the inner mechanism during different dehydration therapies such as mannitol injection and hypertonic saline. The investigators used a self-made near infrared spectroscopy (NIRS) instrument to monitor the physiological changes noninvasively including oxyhemoglobin (\[HbO2\]), deoxy-hemoglobin (\[Hb\]), the derived change in blood volume (\[tHb\]) and water concentration on the forehead of brain edema patients.

Conditions

  • Hemodynamic Instability
  • Water on the Brain
  • Intracranial Pressure Increase

Interventions

PROCEDURE

Mannitol injection

Standard mannitol injection to decrease intracranial pressure of patients

PROCEDURE

Hypertonic saline injection

Standard Hypertonic saline injection to decrease intracranial pressure of patients

Sponsors & Collaborators

  • Affiliated Hospital of Armed Police Logistics College

    collaborator UNKNOWN

  • Ting Li

    lead UNKNOWN

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-09-01
Primary Completion
2019-11-01
Completion
2019-12-11

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03828032 on ClinicalTrials.gov