Cerebral Hemodynamic Effects of Hypertonic Solutions in Severely Head-Injured Patients
NCT00125229 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 10
Last updated 2012-06-26
Summary
This is a clinical study comparing the physiologic effects of two hypertonic solutions (mannitol, hypertonic saline) with a particular emphasis on changes in cerebral blood flow in patients with intracranial hypertension following serious traumatic brain injury (TBI).
Conditions
- Traumatic Brain Injury
- Intracranial Hypertension
Interventions
- DRUG
-
Mannitol
- DRUG
-
Hypertonic Saline
Sponsors & Collaborators
-
The University of Texas Health Science Center at San Antonio
lead OTHER
Principal Investigators
-
Roman Hlatky, M.D. · Center for Neurosurgical Sciences - UTHSC San Antonio
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-08-31
- Primary Completion
- 2006-06-30
- Completion
- 2006-06-30
Countries
- United States
Study Locations
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