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Controling Mean Arterial Pressure Using a Closed-Loop System for Vasopressor Titration

NCT04586218 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2020-12-22

No results posted yet for this study

Summary

The investigators have developed an automated vasopressor controller to improve the titration of vasopressor in order to maintain mean arterial pressure (MAP) within a narrow range and have recently shown the controller was effective in both the operating room and intensive care unit. The controller has been used recently in a case series of three patients undergoing cardiac surgery and in five patients after cardiac surgery.

The investigators want to compare now a manual to a closed-loop titration of vasopressor infusion in patients admitted in the Intensive Care unit after cardiac surgery

Conditions

  • Cardiac Surgery

Interventions

BEHAVIORAL

Computer guided vasopressor infusion

automated titration of vasopressor infusion to maintain a mean arterial pressure \> 65mmHg

BEHAVIORAL

Manual control of vasopressor infusion

manual adjustments of noradrenaline infusion

Sponsors & Collaborators

  • Bicetre Hospital

    collaborator OTHER

  • Erasme University Hospital

    collaborator OTHER

  • Clinique de la Sauvegarde

    lead OTHER

Principal Investigators

  • Olivier Desebbe, MD · Clinique de la Sauvegarde

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-11-26
Primary Completion
2020-12-17
Completion
2020-12-17

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04586218 on ClinicalTrials.gov