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Endotoxin and Intestinal Flora Before and After Gastric Bypass or Banding in Diabetics

NCT00960765 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2016-01-28

No results posted yet for this study

Summary

This research project is designed to investigate endotoxin (a toxin present in the wall of certain kinds of bacteria) levels and the type of bacteria present in the intestine before and after Roux-en-Y gastric bypass or gastric banding surgery in patients that meet the classification for morbid obesity (body mass index \>40 kg/m2) and type 2 diabetes. It is known that the type of bacteria present in the intestines of normal weight and obese individuals are different, and it is also known that people with obesity and type 2 diabetes have higher levels of endotoxin. It has been shown that the bacteria change over the long run after Roux-en-Y gastric bypass surgery, but the short-term effects are not known and the endotoxin levels after this procedure have never been studied.

Conditions

  • Obesity, Morbid
  • Diabetes Mellitus, Type 2
  • Gastric Bypass

Sponsors & Collaborators

  • Synergy Bariatrics

    collaborator UNKNOWN

  • Sisters of Charity Hospital

    collaborator UNKNOWN

  • The New York State Center of Excellence in Bioinformatics & Life Sciences

    collaborator OTHER

  • CPL Associates

    lead OTHER

Principal Investigators

  • Joseph A Caruana, M.D. · Synergy Bariatrics

Eligibility

Min Age
18 Years
Max Age
95 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-08-31
Primary Completion
2015-04-30
Completion
2015-04-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00960765 on ClinicalTrials.gov