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The Prevalence of Thiamin Deficiency in Ambulatory Patients With Heart Failure

NCT00953823 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 110

Last updated 2012-12-24

No results posted yet for this study

Summary

Patients with heart failure are at an increased risk for thiamin deficiency (TD), for many reasons such as malnutrition and the use of diuretic drugs. Thiamin is a B vitamin that plays an important role in the production of energy in body. Therefore, low levels of thiamin may limit the amount of energy available for the heart to pump blood. Recent thiamin supplementation trials have demonstrated significant improvements in heart function. However, while clinically important, the results of these studies are limited by their small sample sizes, indirect measurement of thiamin status and reliance on hospitalized patients. Therefore, the investigators' goal is to determine the prevalence of thiamin deficiency in ambulatory patients with heart failure by direct measurement of thiamin in red blood cells.

Conditions

Sponsors & Collaborators

  • Canadian Foundation for Dietetic Research (CFDR)

    collaborator OTHER

  • Unity Health Toronto

    lead OTHER

Principal Investigators

  • Mary Keith, PhD, RD · Unity Health Toronto

  • Andrew Yan, MD · Cardiologist, St. Michael's Hospital

  • Abdul Al-Hesayen, MD · Cardiologist, St. Michael's Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-05-31
Primary Completion
2012-11-30
Completion
2012-12-31

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00953823 on ClinicalTrials.gov