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Peripheral Effects of Endotoxin on Insulin Resistance

NCT00929136 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 8

Last updated 2010-10-04

No results posted yet for this study

Summary

The aim of the study is to isolate the direct effects of endotoxin on glucose, lipid and protein metabolism. Eight healthy volunteers are enrolled. The hypothesis is that endotoxin will induce insulin resistance, lypolysis and proteolysis acutely.

Conditions

  • Healthy

Interventions

BIOLOGICAL

USP endotoxin

Continuous intra-arterial infusion

Sponsors & Collaborators

  • Aarhus University Hospital

    lead OTHER

Principal Investigators

  • Mads Buhl, M.D. · Medical Department M (Endocrinology and Diabetes), Århus University Hospital, Denmark

  • Niels Moller, M.D., professor, Dmsc · Medical Department M (Endocrinology and Diabetes), Aarhus University Hospital, Denmark

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-06-30
Primary Completion
2010-05-31
Completion
2010-05-31

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00929136 on ClinicalTrials.gov