Hepatic Metabolic Changes in Response to Glucagon Infusion
NCT03526445 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 27
Last updated 2019-08-06
Summary
The objective of the study is to investigate how exogenously administered glucagon affects hepatic lipid, glucose and protein metabolism as well as appetite, food intake and resting energy expenditure.
Conditions
- Non-Alcoholic Fatty Liver Disease
- Total Pancreatectomy
- Diabetes Mellitus
Interventions
- DRUG
-
Glucagon
Glucagon (4 ng/kg/min)
- DRUG
-
Saline
Placebo
Sponsors & Collaborators
-
University of Copenhagen
collaborator OTHER -
Steno Diabetes Center Copenhagen
lead OTHER
Principal Investigators
-
Filip Krag Knop, Prof. · Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 30 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-05-01
- Primary Completion
- 2019-06-12
- Completion
- 2019-06-12
Countries
- Denmark
Study Locations
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