Stage-specific Case Management for Early Psychosis

Summary

One of the commonly adopted strategies in improving outcome in psychotic disorders is by focused, specific and intensive intervention in the initial few years of the disorder. However the effects of intervention and the optimal duration of intervention have seldom been examined in randomized studies. This study uses a randomized controlled study design to investigate the effectiveness of stage-specific case-management in improving outcome of first episode psychotic disorders. It also addresses whether two years of case-management is less effective than four years of case-management over a four year period. A total of 360 subjects, who aged 25 above, and diagnosed with first episode psychotic disorders, will be and randomized into 3 groups: (1) standard care alone without case management, (2) two-year case management, (3) four-year case management. All groups will receive usual standard care treatment. This four-year follow-up study will assess symptoms, functioning, quality of life as well as health economics data.

Conditions

• Psychotic Disorders

Interventions

BEHAVIORAL

stage-specific case-management

Stage-specific case-management for psychosis by designated key-workers according to specified protocol

Sponsors & Collaborators

• Queen Mary Hospital, Hong Kong

  collaborator OTHER

• Kwai Chung Hospital

  collaborator OTHER

• Kowloon Hospital, Hong Kong

  collaborator OTHER

• Castle Peak Hospital

  collaborator OTHER_GOV

• Shatin Hospital

  collaborator OTHER

• Tai Po Hospital

  collaborator OTHER_GOV

• North District Hospital, Hong Kong

  collaborator UNKNOWN

• United Christian Hospital

  collaborator OTHER

• Queen Elizabeth Hospital, Hong Kong

  collaborator OTHER

• The University of Hong Kong

  lead OTHER

Principal Investigators

• Eric YH Chen, MD · The University of Hong Kong

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

26 Years

Max Age

55 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2009-06-30

Primary Completion

2015-12-31

Completion

2015-12-31

Countries

• China

Study Locations