Specialized Treatment Early in Psychosis (STEP)

Summary

The purpose of this study is to understand the effectiveness of a specialized package of phase-specific treatments for individuals in the midst of their first episode of psychosis. The pharmacologic and psychosocial treatments will be delivered within a state public mental health center.

Conditions

• Schizophrenia and Disorders With Psychotic Features

Interventions

BEHAVIORAL

Cognitive Behavioral Group Therapy

once per week

BEHAVIORAL

Cognitive remediation

as needed

DRUG

Medications

Individualized prescription of psychotropic medications including but not restricted to antipsychotic, antidepressant and mood stabilizers.

BEHAVIORAL

MFG

Multi-Family psychoeducation Group based on the model published by McFarlane et al.

BEHAVIORAL

Assertive case management

Meetings with an individual clinician (social work or nursing) who provides supportive psychotherapy, helps assist with vocational and educational supports.

OTHER

Treatment as Usual in the community

Subjects randomized to this arm either return to their existing outpatient psychiatrist or, if they do not have one yet, are referred by the clinic to preferred providers in the community. The nature of the interventions provided is variable and is being monitored by the research clinic.

Sponsors & Collaborators

• Yale University

  lead OTHER

Principal Investigators

• Vinod H Srihari, M.D. · Yale University School of Medicine & Connecticut Mental Health Center

• Scott Woods, M.D. · Yale University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

16 Years

Max Age

45 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2006-03-31

Primary Completion

2013-08-31

Completion

2013-08-31

Countries

• United States

Study Locations