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Does APOE-e4 Predict Delirium and Cognitive Dysfunction After Surgery?

NCT00911677 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2009-06-02

No results posted yet for this study

Summary

Patients with the APOE-ε4 genotype are at increased risk of both vascular dementia and peripheral vascular disease. Patients undergoing major vascular surgery are at particularly high risk of delirium and other, more subtle, changes in cognitive function following surgery. The hypothesis of this trial is that the APOE-ε4 genotype is associated with both delirium and postoperative cognitive dysfunction (POCD).

Conditions

  • Delirium
  • Postoperative Cognitive Dysfunction

Sponsors & Collaborators

  • Canadian Anesthesiologists' Society

    collaborator OTHER

  • University of Ottawa

    collaborator OTHER

  • Ottawa Hospital Research Institute

    lead OTHER

Principal Investigators

  • Gregory L Bryson, MD, FRCPC · Department of Anesthesiology, The Ottawa Hospital

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-08-31
Primary Completion
2008-03-31
Completion
2009-05-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00911677 on ClinicalTrials.gov