Semantic Memory, Financial Capacity, and Brain Perfusion in Mild Cognitive Impairment (MCI) (CASL)
NCT00880555 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 78
Last updated 2016-03-24
Summary
Alzheimer's disease (AD) often manifests as a memory disorder before dementia develops. Dementia is considered to be present when a person can no longer handle complex activities of daily living, such as managing finances. This study will investigate the relationship between changes in the ability to manage finances and brain perfusion, which will be measured using continuous arterial spin-labeling (an experimental MRI). Subjects will also undergo neuropsychological tests focusing on several types of memory and thought process, with special emphasis on semantic memory. An important question to be addressed is whether changes in function are better predicted by the neuropsychological tests or by the brain scan.
Conditions
- Alzheimer Disease
- Dementia
Sponsors & Collaborators
-
University of Alabama at Birmingham
collaborator OTHER -
VA Office of Research and Development
lead FED
Principal Investigators
-
David G Clark, MD · Birmingham VA Medical Center, Birmingham, AL
Eligibility
- Min Age
- 50 Years
- Max Age
- 89 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2009-04-30
- Primary Completion
- 2014-05-31
- Completion
- 2014-05-31
Countries
- United States
Study Locations
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